Bioinformatics Group

Institute of Molecular Biology NAS RA

Lilit Nersisyan

l_nersisyanLilit Nersisyan, PhD

 +374(94) 601703
Curriculum vitae


Bioinformatics Researcher
Group of Bioinformatics, Institute of Molecular Biology NAS RA
(2016 – now)

Adjunct lecturer
Introduction to Biosciences
American University of Armenia

PhD student
Group of Bioinformatics, Institute of Molecular Biology NAS RA
(2014 – 2017)

Junior Bioinformatics Researcher
Group of Bioinformatics, Institute of Molecular Biology NAS RA
(2011 – 2016)

Teaching Associate
American University of Armenia
(2014 – 2016)

Java Developer (remote)
Communify Health, New York, USA

Research Assistant
Group of Immunoregulation, Insitute of Molecular Biology NAS RA


PhD in Information Sciences (Bioinformatics)
Institute of Molecular Biology NAS RA,  University of Leipzig (degree granted by)

Thesis: “Telomere analysis based on high-throughput multi-omics data” PDF

Master’s degree in Computer and Information Science
American University of Armenia

Master’s degree in Biotechnology
International Scientific and Educational Center, NAS, RA

Bachelor’s degree in Biophysics
Faculty of Biology, Yerevan State University

Research interests

Telomere bioinformatics
Pathway signal flow analysis
Mining the next generation sequencing data for systems biology research

Research grants and fellowships

EMBO Short term research fellowship
Three months research stay at Leibniz Institute on Aging (Rudolph group), FLI, Jena, Germany, 2017

DAAD Short Term Research Fellowship
Four months research stay in the Interdisciplinary Centre for Bioinformatics (Binder group), University of Leipzig, Leipzig, Germany, 2015

PSFC: pathway signal flow calculator (PI)
Research Grant molbio-3818 from The Armenian National Science and Education Fund (ANSEF), 2015

PSFC: a Cytoscape app for calculating pathway signal flows (student) 
Google Summer of Code 2014

Selected publications

  1. Arsen Arakelyan , Lilit Nersisyan, David Poghosyan, Lusine Khondkaryan, Anna Hakobyan, Henry Löffler-Wirth, Evie Melanitou, Hans Binder. Autoimmunity and autoinflammation: A systems view on signaling pathway dysregulation profiles. PLoS One 2017. 12(11):e0187572.

  2. Nersisyan L, Arakelyan A. A transcriptome and literature guided algorithm for reconstruction of pathways to assess activity of telomere maintenance mechanisms. bioRxiv 200535.  doi:

  3. Binder H., Hopp L., et al. Genomic and transcriptomic heterogeneity of colorectal tumors arising in Lynch Syndrome. J. Pathol. 2017. PubMed Full text

  4. Nersisyan L. Integration of Telomere Length Dynamics into Systems Biology Framework: A Review. Gene Regul Syst Bio. 2016, 10:35-42. PubMed  Full text

  5. Arakelyan A, Nersisyan L, Hakobyan A. Application of MATLAB in -Omics and Systems Biology.  Applications from Engineering with MATLAB Concepts, Associate Prof. Jan Valdman (Ed.), ISBN: 978-953-51-2459-7. InTech, Croatia, 2016. DOI: 10.5772/62847.   Full text

  6. Arakelyan A, Nersisyan L, Petrek M, Löffler-Wirth H, Binder H. Cartography of pathway signal perturbations identifies distinct molecular pathomechanisms in malignant and chronic lung diseases. Front. Genet. 2016, 7:79. PubMed  Full text

  7. Nersisyan L, Löffler-Wirth H, Arakelyan A, Binder H. Gene Set- and Pathway- Centered Knowledge Discovery Assigns Transcriptional Activation Patterns in Brain, Blood, and Colon Cancer: A Bioinformatics Perspective. Int. J. of Knowl. Disc. in Bioinf. (IJKDB) 2016, 4(2):46-49. Full text

  8. Hakobyan A, Nersisyan L, Arakelyan A. Quantitative trait association study for mean telomere length in the South Asian Genomes. Bioinformatics 2016, 32(11):1697-700. PubMed   Full text

  9. Hopp L, Nersisyan L, Löffler-Wirth H, Arakelyan A, Binder H. Epigenetic heterogeneity of B-cell lymphoma: Chromatin modifiers. Genes 2015, 6(4):1076-1112. PubMed   Full text

  10. Nersisyan L, Johnson G, Riel-Mehan M et al. PSFC: a Pathway Signal Flow Calculator App for Cytoscape [version 1; referees: 1 approved] F1000Research 2015, 4:480.   PubMed Full text

  11. Nersisyan L, Arakelyan A. Computel: computation of mean telomere length from whole-genome next-generation sequencing data. PLoS One 2015, 10(4):e0125201. PubMed Full text

  12. Nersisyan L, Samsonyan R, Arakelyan A. CyKEGGParser: tailoring KEGG pathways to fit into systems biology analysis workflows. Version 2. F1000Res 2014, 3:145. PubMed   Full text

  13. Arakelyan A, Nersisyan L. KEGGParser: parsing and editing KEGG pathway maps in Matlab. Bioinformatics 2013 Feb 15;29(4):518-9. PubMed   Full text