Bioinformatics Group

Institute of Molecular Biology NAS RA

Siras Hakobyan

s_hakobyanSiras Hakobyan, PhD student

Junior researcher

 s_hakobyan@mb.sci.am
 +374(94) 319007
Curriculum vitae

Experience

Junior researcher
Group of Bioinformatics, Institute of Molecular Biology NAS RA
(2019 – now)


Research assistant
Group of Bioinformatics, Institute of Molecular Biology NAS RA
(2017 – 2019)


Trainee
Group of Bioinformatics, Institute of Molecular Biology NAS RA
(2016 – 2017)

Education


PhD studnet
Institute of Molecular Biology NAS RA
(2019-now)


Master’s degree in Bioinformatics
Faculty of Biology, Yerevan State University
(2016-2018)


Bachelor’s degree in Bioinformatics
Faculty of Biology, Yerevan State University
(20010-2016)

Research interests

Cancer bioinformatics
Pathway analysis
NGS data analysis

Research grants and fellowships


DAAD Short Term Research Fellowship
Six months research stay in the Interdisciplinary Centre for Bioinformatics (Binder group), University of Leipzig, Leipzig, Germany, 2019


Development of pathway-based drug repositioning platform
Internal grant of Russian-Armenian University, 2018-2019


Mechanisms underlying resistance of BRCA1-deficient ovarian cancers to PARP-inhibitors
18RF-112 State Committee of Sciences (SCS) of Armenia, 2018-2020

oBIG:Partner Initiative in Bioinformatics, Systems Medicine and Health
Federal Ministry of Education and Research, Germany, 2017-2019


Selected publications

Arakelyan, A., Nersisyan, L., Nikoghosyan, M., Hakobyan, S., Simonyan, A., Hopp, L., Loeffler-Wirth, H., & Binder, H. (2019). Transcriptome-guided drug repositioning. Pharmaceutics. https://doi.org/10.3390/pharmaceutics11120677

Hodorová, V., Lichancová, H., Zubenko, S., Sienkiewicz, K., Penir, S. M. U., Afanasyev, P., Boceck, D., Bonnin, S., Hakobyan, S., Smyczynska, U., Zhivkoplias, E., Zlatohurska, M., Tralle, E., Frolova, A., Pryszcz, L. P., Brejová, B., Vinař, T., & Nosek, J. (2019). Genome Sequence of the Yeast Saprochaete ingens CBS 517.90. Microbiology Resource Announcements. https://doi.org/10.1128/mra.01366-19

Lichancová, H., Hodorová, V., Sienkiewicz, K., Penir, S. M. U., Afanasyev, P., Boceck, D., Bonnin, S., Hakobyan, S., Krawczyk, P. S., Smyczynska, U., Zhivkoplias, E., Zlatohurska, M., Odrzywolski, A., Tralle, E., Frolova, A., Pryszcz, L. P., Brejová, B., Vinař, T., & Nosek, J. (2019). Genome Sequence of Flavor-Producing Yeast Saprochaete suaveolens NRRL Y-17571 . Microbiology Resource Announcements. https://doi.org/10.1128/mra.00094-19

Nikoghosyan, M., Hakobyan, S., Hovhannisyan, A., Loeffler-Wirth, H., Binder, H., & Arakelyan, A. (2019). Population levels assessment of the distribution of disease-associated variants with emphasis on Armenians – A machine learning approach. Frontiers in Genetics. https://doi.org/10.3389/fgene.2019.00394